allura red ac solubility
Published by on November 13, 2020
Male FVB mice were given a single intra-peritoneal injection of various doses of Allura Red AC and sacrificed at 46 h after treatment. Allura Red AC (FD&C Red #40) is a colorant. Press calculate Allura Red AC, a food colourant, is dark red and water-soluble powder or granules used in various applications, such as in drinks, syrups, sweets and cereals. Reagents, Inhibitor disodium;6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate, CC1=CC(=C(C=C1S(=O)(=O)[O-])OC)N=NC2=C(C=CC3=C2C=CC(=C3)S(=O)(=O)[O-])O.[Na+]. More... Validated by Experts, Validated by Users, Non-Validated, Removed by Users. Amaranth (E123) and Allura red (E129), very important food azo dyes used in food, drug, paper, cosmetic and textile industries, were assessed for their genotoxic potential through comet assay in yeast cells. Still be ensured that TCI does everything to protect its customers. Blood samples were collected and the frequency of micronucleated polychromatic erythrocytes (fMNPCE) and the cell proliferation (%PCE) was determined. �K���1c`��u]����ku�k�m�%��1N����a��������u=�M/60t0p40�vt40�� F��� �рn6�\A����4��]� ���z�����E��0���Y�Y���i�d��p�o�s��:7��/H20�z���n i)�=��4���8� Blood samples were collected and the frequency of micronucleated polychromatic erythrocytes (fMNPCE) and the cell proliferation (%PCE) was determined. a stock solution of known concentration. Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. Male FVB mice were given a single intra-peritoneal injection of various doses of Allura Red AC and sacrificed at 46 h after treatment. Copyright © 2017 ChemicalBook All rights reserved. %PDF-1.5 %���� Food Red 17. Amaranth (E123) and Allura Red AC (E129), very important food azo dyes used in food, drug, paper, cosmetic and textile industries, were assessed for their genotoxic potential through comet assay in yeast cells. GC-MS analysis confirmed the cleavage of the -N=N- bond with formation of two main aromatics in SO4(2-) medium and three chloroaromatics in Cl(-) solutions. Disodium 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-2-naphthalenesulfonate, 2-naphthalenesulfonic Acid, 6-hydroxy-5-[(6-methoxy- The tested doses were 0, 100, 200, 400, 600, 800, 1000, 1500, and 2000 mg/kg body weight (b.w.). The negative values of the thermodynamic parameters DeltaG, DeltaH, and DeltaS indicated that hydrogen bond and van der Waals forces are dominant in the binding between the food colourant and HSA. The oxidation ability increased in the sequence EO-H2O2 < EF < PEF and faster degradation was always obtained using BDD. Allura Red AC (FD&C Red #40) is a colorant. More... Validated by Experts, Validated by Users, Non-Validated, Removed by Users. Tip: Chemical formula is case sensitive: If released to air, Allura Red AC dye will exist solely in the particulate phase in the atmosphere since it is a salt and will be nonvolatile. CONCLUSIONS:The CD and Raman spectra showed that the binding of Allura Red AC to HSA induces the rearrangement of the carbonyl hydrogen-bonding network of polypeptides, which changes the HSA secondary structure. The effective oxidation of final oxalic and oxamic acids by BDD along with the photolysis of Fe(III)-oxalate species by UVA light accounted for the superiority of PEF with BDD. Please make sure the liquid is clear before adding the next TCI utilise des cookies pour personnaliser et améliorer votre expérience utilisateur. ( < 1 mg/ml refers to the product slightly soluble or insoluble ), Safe and effective drug dosing is necessary, regardless of its purpose of administration. Si vos informations sont correctes et que vous ne pouvez toujours pas visualiser la FDS demandée, Products, Signaling ����� �� � �= determine the rest. Vous pouvez vous désabonner à tout moment. TCI wishes to warn its customers about the possibility of such fraudulent activities. At 37°C the minimum concentration of Amaranth and Allura Red AC at which significant DNA damage observed through comet assay was 1,250 μg/mL in 2nd h post exposure time. carbon-12) En poursuivant votre navigation sur notre site, vous acceptez l'utilisation de cookies. +Add Attachment The main oxidants were hydroxyl radicals formed at the anode surface from water oxidation and in the bulk from Fenton's reaction between H2O2 and added Fe(2+). The purity of Allura Red AC is specified as not less than 85% of total colouring matters, calculated as the disodium salt, and not more than 15% total amount of volatile matter (loss on drying at 135 To calculate molar mass of a chemical compound, please enter its chemical formula and click The dilution calculator is a useful tool which allows you to calculate how to dilute Comet assay was standardized by with different concentration of H(2)O(2). Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed In this study we have evaluated whether Allura Red is genotoxic using a flow cytometer-based micronucleus assay in peripheral blood of mice. No significant genotoxic activity was observed for Amaranth and Allura red at 28 degrees C but at 37 degrees C direct relation of Amaranth concentration with comet tail was significant and no positive relation was seen with time exposure factor. Male FVB mice were given a single intra-peritoneal injection of various doses of Allura Red and sacrificed at 46 h after treatment. endstream endobj 579 0 obj <. Allura Red AC Dye. An example of a dilution calculation using the Tocris dilution calculator TCI utilise des cookies pour personnaliser et améliorer votre expérience utilisateur. Warning: TCI has been made aware of false correspondence being circulated via e-mail. NH4(+), NO3(-) and SO4(2-) ions were released during the mineralization. Enter 20 into the Volume (final) box and select the correct unit (milliliter) The decolorization and mineralization of solutions containing 230 mg L(-1) of the food azo dye Allura Red AC at pH 3.0 have been studied upon treatment by electrochemical oxidation with electrogenerated H2O2 (EO-H2O2), electro-Fenton (EF) and photoelectro-Fenton (PEF).METHODS AND RESULTS: Experiments were performed with a stirred tank reactor containing a boron-doped diamond (BDD) or Pt anode and an air-diffusion cathode to generate H2O2. The effective oxidation of final oxalic and oxamic acids by BDD along with the photolysis of Fe(III)-oxalate species by UVA light accounted for the superiority of PEF with BDD. Enter 50 into the Concentration (final) box and select the correct unit (micromolar) METHODS AND RESULTS:Binding interaction of human serum albumin (HSA) with Allura Red AC, a food colourant, was investigated at the molecular level through fluorescence, ultraviolet-visible, circular dichroism (CD) and Raman spectroscopies, as well as protein-ligand docking studies to better understand the chemical absorption, distribution and transportation of colourants. Disodiumsaltof2-hydroxy-1-(2-methoxy-5-methyl-4-sulfonatophenylazo)naphthalene-6-sulfonate. The tested doses were 0, 100, 200, 400, 600, 800, 1000, 1500, and 2000 mg/kg body weight (b.w.). Instructions to calculate molar mass (molecular weight) of a chemical compound: Amaranth (E123) and Allura Red AC (E129) were found to exhibit their genotoxic effect directly in Saccharomyces cerevisiae. Allura Red AC has the ability to quench the intrinsic fluorescence of HSA through static quenching. Get our product updates and special offers! Allura Red AC dye's production and use as a color additive in foods, drugs and cosmetics may result in its release to the environment through various waste streams. Each dose group constituted three mice, except for in the dose group of 1000 mg/kg b. w., which constituted four mice. PEF process with BDD yielded almost total mineralization following similar trends in SO4(2-), ClO4(-) and NO3(-) media, whereas in Cl(-) medium, mineralization was inhibited by the formation of recalcitrant chloroderivatives[1], mass of a compound required to prepare a solution of known volume and concentration, volume of solution required to dissolve a compound of known mass to a desired concentration, concentration of a solution resulting from a known mass of compound in a specific volume.
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